SCP2025
May 27 - 28, 2025 | Boston, USA
Hands-on workshop on May 29, 2025
Workshop attendance is separate from the conference. Save your spot by signing up with the workshop registration form.
Register Program Speakers Sponsors
The 8th Single Cell Proteomics Conference (SCP2025) will be held at Northeastern University in Boston, USA. It will be at Northeastern University in the John D. O’Bryant building, 1st floor (40 Leon Street).
Register and submit abstracts
Abstract deadline: April 1, 2025
Deadline: May 20, 2025
Reserve a hotel
Deadline: May 26, 2025
Program
Tuesday May 27
The day will start with a primer and overview of current trends in single-cell mass spec proteomics. Then we will transition to talks and discussions. As usual for the meeting, we will have ample time for formal and informal discussions.
Breakfast and lunch will be provided on site.
| Speaker | Title | ET | GMT | Your local time |
| Registration and breakfast | 8:30 | 12:30 | ||
| Opening remarks | 9:00 | 13:00 | ||
| Galit Lahav, Harvard Medical School | Information Transfer through Integration of Protein Dynamics and Modifications | 9:10 | 13:10 | |
| Discussion | 9:25 | 13:25 | ||
| Andrew Leduc, Northeastern University | Regulation of protein synthesis and degradation in a mammalian tissue at single cell resolution | 9:35 | 13:35 | |
| Discussion | 10:05 | 14:05 | ||
| General discussion & Coffee Break | 10:20 | 14:20 | ||
| Jeroen Krijgsveld, Heidelberg University | Decoding adaptive drug resistance to KRAS-G12C inhibition through nascent and single cell proteomics | 11:00 | 15:00 | |
| Discussion | 11:25 | 15:25 | ||
| Christoph Krisp, Bruker Daltonics GmbH & Co. KG | Low input spatial proteomics at scale using Evosep Whisper Zoom on the timsTOF Ultra 2 | 11:35 | 15:30 | |
| Discussion | 11:50 | 15:50 | ||
| Lunch & Poster Session 1 | 12:00 | 16:00 | ||
| Ryan Kelly, Brigham Young University | An in-depth, label-free single-cell proteome every 5 minutes | 1:30 | 17:30 | |
| Discussion | 2:00 | 18:00 | ||
| Yash Shukla, University of Texas at Austin | Landscape and regulation of new protein translation in the early C. elegans embryo | 2:15 | 18:15 | |
| Discussion | 2:25 | 18:25 | ||
| Jared O. Kafader, Northwestern University | Probing the proteome of differentiating human skin keratinocytes using single nuclei proteoform imaging | 2:30 | 18:30 | |
| Discussion | 2:40 | 18:40 | ||
| Boryana Petrova, MediUni Vienna | Towards Single Cell High Throughput Metabolomics | 2:45 | 18:45 | |
| Discussion | 2:55 | 18:55 | ||
| Coffee Break & Poster session | 3:00 | 19:00 | ||
| Alexey Nesvizhskii, University of Michigan | Analysis of single-cell and low-input proteomics data using FragPipe | 4:00 | 20:00 | |
| Discussion | 4:30 | 20:30 | ||
| Justin Walley, Iowa State University | Single-cell proteomics differentiates Arabidopsis root cell types | 4:45 | 20:45 | |
| Discussion | 5:05 | 21:05 | ||
| General discussion & Coffee Break | 5:15 | 21:15 | ||
| Georg Wallmann, Max Planck Institute of Biochemistry | Flexible workflows for large scale single-cell processing with alphaDIA | 5:45 | 21:45 | |
| Discussion | 6:05 | 22:05 | ||
| Yuju Chen, Academy Sinica | Nanoscale-to-Single-Cell Phosphoproteomics Uncovers Patient-Level Signaling Networks and Therapeutic Targets | 6:15 | 22:15 | |
| Discussion | 6:35 | 22:35 | ||
| Katie Galloway, MIT | High-resolution profiling reveals coupled transcriptional and translational regulation of transgenes | 6:45 | 22:45 | |
| Discussion | 7:05 | 23:05 |
Wednesday May 28
The day will start with a primer and overview of current trends in single-molecule proteomics. Then we will transition to talks and discussions. As usual for the meeting, we will have ample time for formal and informal discussions.
Breakfast and lunch will be provided on site.
| Speaker | Title | ET | GMT | Your local time |
| Registration and breakfast | 8:30 | 12:30 | ||
| Nikolaus Rajewsky, Max-Delbrück-Center for Molecular Medicine | Spatial RNA & Protein omics – applied to cancer and microplastics | 9:00 | 13:00 | |
| Discussion | 9:15 | 13:15 | ||
| Scott Coyle, University of Wisconsin-Madison | Real-time AM/FM streaming of single cell data using synthetic protein waves | 9:30 | 13:30 | |
| Discussion | 10:00 | 14:00 | ||
| General discussion & Coffee Break | 10:15 | 14:15 | ||
| Panel (Rajewsky, Lahav, & Slavov) | Panel Discussion: Major trends and opportunities | 10:45 | 14:45 | |
| Kevin McDonnell, PTI | JMod: Joint modeling of mass spectra for enhanced multiplexing in the mass and time domains | 11:15 | 15:15 | |
| Discussion | 11:45 | 15:45 | ||
| Lunch & Poster Session 2 | 12:00 | 16:00 | ||
| Jonathan V Sweedler, University of Illinois at Urbana-Champaign | High throughput single cell characterization to unravel cell heterogeneity | 1:30 | 17:30 | |
| Discussion | 2:00 | 18:00 | ||
| Julia Schaepe, Stanford University | Single-molecule states link transcription factor binding to gene expression | 2:15 | 18:15 | |
| Discussion | 2:30 | 18:30 | ||
| Xiaokang Lun, University of Minnesota Twin Cities | Signal amplification by cyclic primer extension enables high-sensitivity single-cell mass cytometry analysis | 2:40 | 18:40 | |
| Discussion | 2:50 | 18:50 | ||
| Bhagyashree Joshi, Delft University of Technology | Protein Fingerprinting Using Multipoint Single-Molecule Structural Analysis | 2:55 | 18:55 | |
| Discussion | 3:05 | 19:05 | ||
| Samantha O'Connor, The Translational Genomics Research Institute | Single Cell Proteomics Captures Proteomic Variation in PBMCs | 3:10 | 19:10 | |
| Discussion | 3:20 | 19:20 | ||
| Coffee Break & Poster session | 3:25 | 19:25 | ||
| Julia Laskin, Purdue University | Advances in High-Resolution Ambient Mass Spectrometry Imaging | 4:00 | 20:00 | |
| Discussion | 4:30 | 20:30 | ||
| Jesse Meyer, Cedars-Sinai Medical Center | High-Throughput Single Muscle Fiber Proteomics Reveals Fiber-Type-Specific Mechanisms of Sarcopenia in Aging Women | 4:45 | 20:45 | |
| Discussion | 5:05 | 21:05 | ||
| Hannah Boekweg, Brigham Young University | Statistical methods for handling cellular heterogeneity in quantitative scMS experiments | 5:15 | 21:15 | |
| Discussion | 5:30 | 21:30 | ||
| Alexander Ivanov, Northeastern University | Porous layer open-tubular (PLOT) columns in pressure- and electric field-driven nano-flow separations enhance proteomic and multi-omic analysis of limited samples, small cell populations, and single cells. | 5:40 | 21:40 | |
| Discussion | 5:55 | 21:55 | ||
| Joel McDade, Quantum-Si | Platinum Pro: Novel Applications of Single Peptide, Single Amino Acid Analysis Using a Small Benchtop Device | 6:05 | 22:05 | |
| Discussion | 6:15 | 22:15 | ||
| Prizes & Closing Remarks | 6:20 | 22:20 | ||
| Dinner for all attendees | TBD | 6:30 | 22:30 |
Thursday May 29 | Workshop
A full day hands-on workshop at PTI will take participants from biological samples through sample preparation via nPOP to mass spectrometry data acquisition and analysis.
- Participation is free with in-person conference registration but requires Workshop Registration. To facilitate interactions and hands-on experience, participation is limited.
Speakers
Presenters include:
- Yu-Ju Chen, Institute of Chemistry Academia Sinica
- Scott Coyle, University of Wisconsin-Madison
- Katie Galloway, MIT
- Galit Lahav, Harvard Medical School
- Julia Laskin, Purdue University
- Ryan Kelly, Brigham Young University
- Jeroen Krijgsveld, Heidelberg University
- Jesse Meyer, Cedars-Sinai Medical Center
- Alexey Nesvizhskii, University of Michigan
- Nikolaus Rajewsky, Berlin Institute for Medical Systems Biology
- Julia Schaepe, Stanford University
- Jonathan Sweedler, University of Illinois Urbana-Champaign
- Chris Tape, University College London
- Olga Vitek, Northeastern University
- Justin Walley, Iowa State University
Sponsors
Platinum sponsors
Gold sponsors
Silver sponsors
